WILLIAM WHITE, MD: Every class of anti-hypertensive drug has some of its own distinct little side effects. Fortunately, the medications have gotten so much better during the last 20 years that we actually see many of the new drugs having no more side effects than placebo pills or sugar pills.
DOMINIC SICA, MD: I would also maybe add that the problem of polypharmacy or multiple prescriptions is such now that most physicians' knowledge of how to give a drug and the wide range of drugs within a specific drug class allow things to be given in a way where side effects are really minimized.
MABEL JONG: Can you outline some success rates from using these drugs, Dr. Sica?
DOMINIC SICA, MD: The success is both immediate and then it's realized long term. The immediate gain is by blood pressure coming under control. The long-term gain will never really be identified in a specific patient, but will be identified in a population sense, so being exposed to these medicines means a lesser risk of developing coronary artery disease, congestive heart failure and likely a lesser progression onto various elements of chronic renal failure.
MABEL JONG: Closing comments, Dr. White?
WILLIAM WHITE, MD: We've learned an awful lot just in the last couple of years about the management of the hypertensive patient with diabetes. We've learned specific new information about certain classes of drugs, and therefore we are able to provide to patients a more refined drug treatment plan, even though it's a lot of drugs, that will actually reduce their morbidity, and that's a very positive thing, considering what we knew a few years ago.
MABEL JONG: A last word from you, Dr. Sica?
DOMINIC SICA, MD: I think the more information we can get to patients about these diseases, so we self-empower them to became active participants in their own health care plan, is the best way we're going to solve this problem. If you educate the patient, you very importantly create the basis for future success with the therapies that you apply.
MABEL JONG: Dr. Sica, Dr. White, thanks for joining us today. And thank you for watching our webcast. I'm Mabel Jong.