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HealthAdvocate

Pregnancy and Childbirth

Treating Asthma During Pregnancy: Choosing the Right Medicine


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Summary & Participants

Drugs receive special scrutiny for safety when used by pregnant women. How do the drugs used to control asthma compare? Listen in as experts explain.

Medically Reviewed On: July 01, 2008

Webcast Transcript


RUSSELL SETTIPANE, MD: The best -- highest category is a category A. Most medications for asthma have been rated category C. There are no category A medications for asthma in pregnancy; the highest rated medications we have are category B.

ANNOUNCER: Among the drugs used to control persistent asthma, the FDA has recently upgraded the safety designation for one of the newer options.

EMILY DIMANGO, MD: Drugs used to combat inflammation, namely inhaled corticosteroids have traditionally been classified as category C. However, recently enough data has been generated to show that inhaled budesonide or Pulmicort may be categorized as B category, meaning that it is safe for babies born to mothers who are taking that drug during pregnancy.

MICHAEL SCHATZ, MD: So in the case of budesonide, this came from the Swedish medical birth registry, where all of the births in Sweden are monitored and registered. And the group of patients -- which numbered over 2500 who took budesonide -- were compared to the hundreds of thousands of women who didn't take budesonide. And they were able to show in that very large number of patients that there were no increased risks in the infants of the mothers taking budesonide.

ANNOUNCER: Doctors say other inhaled corticosteroids, including beclomethasone, triamcinolone, and fluticasone, may prove just as safe, but there are too little data right now to be sure.

There are two non-steroidal anti-inflammatory medications that are category B drugs. But they are generally not considered as effective as inhaled steroids in treating women with asthma.

Safety categorization is just one factor in selecting a therapy. A panel of asthma experts recommended that women should stay on some category C drugs when they become pregnant, if the drug proved effective before the pregnancy began.

Doctors say anyone with persistent asthma should be taking medication. And that includes women, even if they're pregnant. But with a wide range of medication to choose from, doctors say women who are treating their disease should feel confident their unborn child is receiving the best possible care.

EMILY DIMANGO, MD: The good news is that even though poorly controlled asthma can be dangerous to the pregnant mother and to her baby, asthma is relatively easy to control and the drugs that are available to treat asthma have now been shown to be safe for mother and for baby.

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